发明授权
US08337838B2 Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
有权
抗CD70抗体及其用于治疗和预防癌症和免疫疾病的用途
- 专利标题： Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
- 专利标题（中）： 抗CD70抗体及其用于治疗和预防癌症和免疫疾病的用途
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申请号： US12370151申请日： 2009-02-12
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公开(公告)号： US08337838B2公开(公告)日： 2012-12-25
- 发明人: Che-Leung Law , Julie McEarchern , Alan F. Wahl
- 申请人： Che-Leung Law , Julie McEarchern , Alan F. Wahl
- 申请人地址： US WA Bothell
- 专利权人： Seattle Genetics, Inc.
- 当前专利权人： Seattle Genetics, Inc.
- 当前专利权人地址： US WA Bothell
- 代理机构： Alston & Bird LLP
- 主分类号： A61K39/395
- IPC分类号： A61K39/395
摘要：
Disclosed are CD70 binding agents, such as anti-CD70 antibodies and derivatives, that induce a cytotoxic, cytostatic or immunomodulatory without conjugation to a therapeutic agents as well as pharmaceutical compositions and kits comprising the antibody or derivative. Also disclosed are methods for the treatment and prevention of CD70-expressing cancers and immunological disorders comprising administering the CD70 binding agents to a subject.
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