发明授权
- 专利标题： Functionalized nanoceria composition for ophthalmic treatment
- 专利标题（中）： 用于眼科治疗的功能性纳米组合物
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申请号： US13154849申请日： 2011-06-07
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公开(公告)号： US08337898B2公开(公告)日： 2012-12-25
- 发明人: Sudipta Seal , Swanand D. Patil , Manas K. Haldar , Sanku Malik
- 申请人： Sudipta Seal , Swanand D. Patil , Manas K. Haldar , Sanku Malik
- 申请人地址： US FL Orlando
- 专利权人： University of Central Florida Research Foundation, Inc.
- 当前专利权人： University of Central Florida Research Foundation, Inc.
- 当前专利权人地址： US FL Orlando
- 代理机构： Allen, Dyer, Doppelt, Milbrath & Gilchrist, P.A.
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A01N59/16
摘要：
The invention provides a composition comprising a plurality of nanoceria particles, a sufficient amount of at least one inhibitor of human carbonic anhydrase II associated with said plurality of nanoceria particles, and a pharmaceutically acceptable carrier containing said plurality of nanoceria particles with associated inhibitor. One preferred inhibitor of human carbonic anhydrase II comprises 4-carboxybenzene sulfonamide. The disclosed composition is useful in treatment of glaucoma.
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