Invention Grant
- Patent Title: Crystal structure of CD147 extracellular region and use thereof
- Patent Title (中): CD147细胞外区域的晶体结构及其用途
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Application No.: US12674150Application Date: 2007-10-24
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Publication No.: US08338573B2Publication Date: 2012-12-25
- Inventor: Zhinan Chen , Ping Zhu , Xiaoling Yu , Bin Yang , Xiangmin Yang , Zheng Zhang
- Applicant: Zhinan Chen , Ping Zhu , Xiaoling Yu , Bin Yang , Xiangmin Yang , Zheng Zhang
- Applicant Address: CN Xi'an
- Assignee: Zhinan Chen
- Current Assignee: Zhinan Chen
- Current Assignee Address: CN Xi'an
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: CN200710018514 20070821
- International Application: PCT/CN2007/003034 WO 20071024
- International Announcement: WO2009/023995 WO 20090226
- Main IPC: C07K16/00
- IPC: C07K16/00 ; G01N31/00
Abstract:
A crystal, a preparation method and 3D structure of CD147 extracellular region are provided. Such 3D structure is useful in the determination of the active site of CD147 extracellular region by computer modeling or molecular docking method. The crystal and/or 3D structure are useful in a structure-based drug design and the selection of an antibody, a ligand or an interacting molecule of CD 147 extracellular region.
Public/Granted literature
- US20100248974A1 CRYSTAL STRUCTURE OF CD147 EXTRACELLULAR REGION AND USE THEREOF Public/Granted day:2010-09-30
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