发明授权
US08349885B2 Indole and indazole derivatives having a cell-, tissue- and organ-preserving effect
有权
具有细胞,组织和器官保存作用的吲哚和吲唑衍生物
- 专利标题: Indole and indazole derivatives having a cell-, tissue- and organ-preserving effect
- 专利标题(中): 具有细胞,组织和器官保存作用的吲哚和吲唑衍生物
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申请号: US13534682申请日: 2012-06-27
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公开(公告)号: US08349885B2公开(公告)日: 2013-01-08
- 发明人: Soon Ha Kim , Hyoung Jin Kim , Chul Woong Chung , Heui Sul Park , Hyo Shin Kwak , Sung Ho Kim , Jin Gu Park
- 申请人: Soon Ha Kim , Hyoung Jin Kim , Chul Woong Chung , Heui Sul Park , Hyo Shin Kwak , Sung Ho Kim , Jin Gu Park
- 申请人地址: KR Seoul
- 专利权人: LG Life Sciences Ltd.
- 当前专利权人: LG Life Sciences Ltd.
- 当前专利权人地址: KR Seoul
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: KR10-2008-0001477 20080104
- 主分类号: A61K31/416
- IPC分类号: A61K31/416 ; A61K31/404 ; C07D231/56 ; C07D209/10
摘要:
The present invention relates to a composition for preserving cells, tissues and organs, comprising as an active ingredient indole and indazole compounds of formula (1), or a pharmaceutically acceptable salt or isomer thereof, which are effective for preventing injury of organs, isolated cell systems or tissues caused by cold storage, transplant operation or post-transplantation reperfusion; a preservation method; and a preparation method of the composition.
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