Invention Grant
US08354307B2 Method for detecting biomolecules electrically and biochip therefor 有权
用于检测生物分子的方法和生物芯片

  • Patent Title: Method for detecting biomolecules electrically and biochip therefor
  • Patent Title (中): 用于检测生物分子的方法和生物芯片
  • Application No.: US12922934
    Application Date: 2009-01-20
  • Publication No.: US08354307B2
    Publication Date: 2013-01-15
  • Inventor: Jae-Hoon Lee
  • Applicant: Jae-Hoon Lee
  • Applicant Address: KR Seoul
  • Assignee: Digital Genomics Inc.
  • Current Assignee: Digital Genomics Inc.
  • Current Assignee Address: KR Seoul
  • Agency: Lucas & Mercanti, LLP
  • Priority: KR10-2008-0027099 20080324
  • International Application: PCT/KR2009/000285 WO 20090120
  • International Announcement: WO2009/119971 WO 20091001
  • Main IPC: G01N15/06
  • IPC: G01N15/06 G01N33/00 G01N33/48
Method for detecting biomolecules electrically and biochip therefor
Abstract:
The present invention relates to a method for detecting the presence and/or the reaction of a biomolecule by monitoring changes of electrical property accurately according to the biological, biochemical or chemical reaction of the biomolecule, and a biochip provided for this purpose. The present invention provides a method for detecting the presence and/or the reaction of a biomolecule in a target sample, wherein the reaction of the target sample is performed under known reaction solution, in which a reference fluid having a high dielectric constant such as water is filled into a reaction chamber before the reaction to measure an impedance value or a capacitance value, after completing the reaction, the reaction solution is removed and said reference fluid having a high dielectric constant is refilled to measure an impedance value or a capacitance value, and then the impedance value or the capacitance value measured before and after the reaction is compared with each other.
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