发明授权
- 专利标题： Methods for stimulating an immune response using bacterial antigen delivery system
- 专利标题（中）： 使用细菌抗原递送系统刺激免疫应答的方法
-
申请号： US12083188申请日： 2006-10-03
-
公开(公告)号： US08357373B2公开(公告)日： 2013-01-22
- 发明人: Lloyd J. Old , Gerd Ritter , Hiroyoshi Nishikawa , Sacha Gnjatic , Jorge E. Galan
- 申请人： Lloyd J. Old , Gerd Ritter , Hiroyoshi Nishikawa , Sacha Gnjatic , Jorge E. Galan
- 申请人地址： US NY New York US CT New Haven
- 专利权人： Ludwig Institute for Cancer Research,Yale University
- 当前专利权人： Ludwig Institute for Cancer Research,Yale University
- 当前专利权人地址： US NY New York US CT New Haven
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 国际申请： PCT/US2006/038804 WO 20061003
- 国际公布： WO2007/044406 WO 20070419
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A01N63/00
摘要：
The invention relates to the use of the type III secretion system of bacteria to stimulate immune responses against tumor antigen(s) for treating antigen-loss variant tumors. Methods are provided for stimulating and/or increasing an immune response against tumor antigens. The invention also relates to the preparation of antigen presenting cells from peripheral blood mononuclear cells using bacteria having a type III secretion system.
公开/授权文献
信息查询
