Invention Grant
- Patent Title: Ansamycin formulations and methods of use thereof
- Patent Title (中): 安沙霉素制剂及其使用方法
-
Application No.: US12229326Application Date: 2008-08-20
-
Publication No.: US08357676B2Publication Date: 2013-01-22
- Inventor: Brian C. Austad , Louis Grenier , Edward B. Holson , John J. Lee , Roger H. Pak , James R. Porter , James L. Wright
- Applicant: Brian C. Austad , Louis Grenier , Edward B. Holson , John J. Lee , Roger H. Pak , James R. Porter , James L. Wright
- Applicant Address: US MA Cambridge
- Assignee: Infinity Discovery, Inc.
- Current Assignee: Infinity Discovery, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Pepper Hamilton LLP
- Agent Thomas J. Engellenner; Reza Mollaaghababa
- Main IPC: A61K31/33
- IPC: A61K31/33 ; A61K31/215 ; A61K31/27

Abstract:
Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 (“Hsp90”).
Public/Granted literature
- US20090069281A1 Ansamycin formulations and methods of use thereof Public/Granted day:2009-03-12
Information query