发明授权
US08357706B2 Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
有权
鞘氨醇1磷酸受体调节剂和手性合成方法
- 专利标题： Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
- 专利标题（中）： 鞘氨醇1磷酸受体调节剂和手性合成方法
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申请号： US12946800申请日： 2010-11-15
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公开(公告)号： US08357706B2公开(公告)日： 2013-01-22
- 发明人: Esther Martinborough , Marcus F. Boehm , Adam Richard Yeager , Junko Tamiya , Liming Huang , Enugurthi Brahmachary , Manisha Moorjani
- 申请人： Esther Martinborough , Marcus F. Boehm , Adam Richard Yeager , Junko Tamiya , Liming Huang , Enugurthi Brahmachary , Manisha Moorjani
- 申请人地址： US CA San Diego
- 专利权人： Receptos, Inc.
- 当前专利权人： Receptos, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Seed IP Law Group PLLC
- 主分类号： A61K31/4245
- IPC分类号： A61K31/4245 ; A61K31/5377 ; A61K31/454 ; C07D271/06 ; C07D413/12
摘要：
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
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