发明授权
US08367695B2 Condensed tetrahydroquinoline derivative and use thereof for medical purposes
失效
缩合四氢喹啉衍生物及其用于医疗目的的用途
- 专利标题： Condensed tetrahydroquinoline derivative and use thereof for medical purposes
- 专利标题（中）： 缩合四氢喹啉衍生物及其用于医疗目的的用途
-
申请号： US12523031申请日： 2008-01-15
-
公开(公告)号： US08367695B2公开(公告)日： 2013-02-05
- 发明人: Masahiro Eda , Tomoko Kuroda , Keiichi Aritomo , Yoshiyuki Aoki , Satoshi Kaneko
- 申请人： Masahiro Eda , Tomoko Kuroda , Keiichi Aritomo , Yoshiyuki Aoki , Satoshi Kaneko
- 申请人地址： JP Osaka-shi
- 专利权人： Mitsubishi Tanabe Pharma Corporation
- 当前专利权人： Mitsubishi Tanabe Pharma Corporation
- 当前专利权人地址： JP Osaka-shi
- 代理机构： Leydig, Voit & Mayer, Ltd.
- 优先权： JP2007-005472 20070115
- 国际申请： PCT/JP2008/050349 WO 20080115
- 国际公布： WO2008/087936 WO 20080724
- 主分类号： A61K31/435
- IPC分类号： A61K31/435 ; A61K31/4355
摘要：
The problem of the present invention is to provide a compound having a GR selective binding activity, which shows less action on other nuclear receptors such as progesterone receptor (PR), mineralocorticoid receptor (MR) and the like. The present invention provides a condensed tetrahydroquinoline compound represented by the following formula (I) wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof or a hydrate thereof.