发明授权
- 专利标题： Process for the synthesis of aryloxypropylamine and heteroaryloxypropylamine
- 专利标题（中）： 芳氧基丙胺和杂芳氧基丙胺的合成方法
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申请号： US12444710申请日： 2007-10-04
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公开(公告)号： US08367868B2公开(公告)日： 2013-02-05
- 发明人: Giorgio Bertolini , Barbara Verzola , Domenico Vergani
- 申请人： Giorgio Bertolini , Barbara Verzola , Domenico Vergani
- 申请人地址： IT Milan
- 专利权人： Archimica S.r.l.
- 当前专利权人： Archimica S.r.l.
- 当前专利权人地址： IT Milan
- 代理机构： ProPat, L.L.C.
- 优先权： ITMI2006A1987 20061016
- 国际申请： PCT/EP2007/060564 WO 20071004
- 国际公布： WO2008/046745 WO 20080424
- 主分类号： C07C209/14
- IPC分类号： C07C209/14
摘要：
The present invention relates to a process for the synthesis of aryloxypropylamine and heteroaryloxypropylamine of formula I: where: A is aryl or heteroaryl, where the aryl is preferably a phenyl, optionally substituted, selected from benzyl and tolyl and the heteroaryl is preferably thiophenyl; Y is an aryl, preferably phenyl, a substituted phenyl or a naphthyl, where the substituted phenyl is preferably selected from tolyl, trihalomethyltolyl and alkoxytolyl, starting from a suitable amino alcohol of formula II:
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