- 专利标题: Protein kinase C inhibitors and uses thereof
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申请号: US12691607申请日: 2010-01-21
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公开(公告)号: US08377924B2公开(公告)日: 2013-02-19
- 发明人: Rajinder Singh , Huí Li , Haoran Zhao , Rao Kolluri , Kin Tso , John Ramphal , Shihai Gu , Carlos Valdez , Jing Zhang , Emily Stauffer , Matthew Duncton , Salvador Alvarez
- 申请人: Rajinder Singh , Huí Li , Haoran Zhao , Rao Kolluri , Kin Tso , John Ramphal , Shihai Gu , Carlos Valdez , Jing Zhang , Emily Stauffer , Matthew Duncton , Salvador Alvarez
- 申请人地址: US CA South San Francisco
- 专利权人: Rigel Pharmaceuticals Inc.
- 当前专利权人: Rigel Pharmaceuticals Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: Bozicevic, Field & Francis LLP
- 代理商 Rudy J. Ng; Carol L. Francis
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; A61K31/497 ; A61K31/535 ; A61K31/505 ; C07D403/10 ; C07D413/12 ; C07D401/12
摘要:
This disclosure concerns compounds which are useful as inhibitors of protein kinase C (PKC) and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC. This disclosure also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
公开/授权文献
- US20100204208A1 PROTEIN KINASE C INHIBITORS AND USES THEREOF 公开/授权日:2010-08-12
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