Invention Grant
- Patent Title: Lonidamine analogues for fertility management
- Patent Title (中): 用于生育管理的罗非胺类似物
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Application No.: US12830681Application Date: 2010-07-06
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Publication No.: US08377958B2Publication Date: 2013-02-19
- Inventor: Ingrid Gunda Georg , Joseph S. Tash , Ramappa Chakrasali , Sudhakar Rao Jakkaraj , Katherine Roby
- Applicant: Ingrid Gunda Georg , Joseph S. Tash , Ramappa Chakrasali , Sudhakar Rao Jakkaraj , Katherine Roby
- Applicant Address: US KS Lawrence
- Assignee: The University of Kansas
- Current Assignee: The University of Kansas
- Current Assignee Address: US KS Lawrence
- Agency: Maschoff Gilmore & Israelsen
- Main IPC: A61K31/416
- IPC: A61K31/416 ; A61K31/437

Abstract:
Fertility management can include: administering to the subject one or more doses of a compound according to Formula I so as to reduce fertility in the subject. Fertility management can also include administering an effective amount of the compound to: impair Sertoli cell function in a male subject; inhibit spermatogenesis in the subject; reduce testis weight in the subject; reduce ovary weight in a female subject; reduce serum progesterone in the female subject; impair ovarian follicle function in the female subject; causing reversible fertility in the subject. In order to return fertility, the method can include ceasing administration of the compound to the subject so as to return fertility in the subject. The compound can be administered for irreversibly sterilizing the subject.
Public/Granted literature
- US20110060003A1 LONIDAMINE ANALOGUES FOR FERTILITY MANAGEMENT Public/Granted day:2011-03-10
Information query
IPC分类: