Invention Grant
- Patent Title: Process for attaching effector molecules to proteins
- Patent Title (中): 将效应分子附着于蛋白质的方法
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Application No.: US11994053Application Date: 2006-06-29
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Publication No.: US08378073B2Publication Date: 2013-02-19
- Inventor: Sam Philip Heywood
- Applicant: Sam Philip Heywood
- Applicant Address: BE
- Assignee: UCB Pharma S.A.
- Current Assignee: UCB Pharma S.A.
- Current Assignee Address: BE
- Agency: McDonnell Boehnen Hulbert & Berghoff
- Priority: GB0513852.4 20050706
- International Application: PCT/GB2006/002416 WO 20060629
- International Announcement: WO2007/003898 WO 20070111
- Main IPC: C07K16/00
- IPC: C07K16/00
Abstract:
The present invention provides a process for attaching one or more effector molecules to one or more cysteines in a protein comprising: a) activating one or more cysteines in the protein by diafiltering the protein against a monothiol reducing agent or a multi-thiol reducing agent which is incapable of forming intramolecular disulphide bonds and b) reacting the treated protein with an effector molecule.
Public/Granted literature
- US20080306246A1 Process for Attaching Effector Molecules to Proteins Public/Granted day:2008-12-11
Information query
