- 专利标题： Substituted azoanthracene derivatives, pharmaceutical compositions, and methods of use thereof
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申请号： US12825631申请日： 2010-06-29
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公开(公告)号： US08383644B2公开(公告)日： 2013-02-26
- 发明人: Adnan M. M. Mjalli , Christopher Behme , Daniel P. Christen , Devi Reddy Gohimukkula , Dharma Rao Polisetti , James Quada , Jennifer L. R. Freeman , Kalpathy Santhosh , Muralidhar Bondlela , Mustafa Guzel , Ravindra Reddy Yarragunta , Robert Carl Andrews , Stephen Thomas Davis , Thomas Scott Yokum
- 申请人： Adnan M. M. Mjalli , Christopher Behme , Daniel P. Christen , Devi Reddy Gohimukkula , Dharma Rao Polisetti , James Quada , Jennifer L. R. Freeman , Kalpathy Santhosh , Muralidhar Bondlela , Mustafa Guzel , Ravindra Reddy Yarragunta , Robert Carl Andrews , Stephen Thomas Davis , Thomas Scott Yokum
- 申请人地址： US NC High Point
- 专利权人： TransTech Pharma, Inc.
- 当前专利权人： TransTech Pharma, Inc.
- 当前专利权人地址： US NC High Point
- 代理商 Samuel B. Rollins
- 主分类号： C07D491/056
- IPC分类号： C07D491/056 ; A61K31/436
摘要：
The present invention is directed to substituted azoanthracene derivatives or pharmaceutically acceptable salts thereof that modulate the human GLP-1 receptor and that may be useful in the treatment of diseases, disorders, or conditions in which modulation of the human GLP-1 receptor is beneficial, such as diabetes mellitus type 2. The invention is also directed to pharmaceutical compositions comprising these compounds and to the use of these compounds and compositions in the treatment of such diseases, disorders, or conditions in which modulation of the human GLP-1 receptor is beneficial.