Invention Grant
US08383785B2 Anti-bacterial activity of 9-hydroxy derivatives of 6,11-bicyclolides
有权
6,11-双环氯化物的9-羟基衍生物的抗细菌活性
- Patent Title: Anti-bacterial activity of 9-hydroxy derivatives of 6,11-bicyclolides
- Patent Title (中): 6,11-双环氯化物的9-羟基衍生物的抗细菌活性
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Application No.: US12437616Application Date: 2009-05-08
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Publication No.: US08383785B2Publication Date: 2013-02-26
- Inventor: Rajesh Iyengar , Yanchun Wang , Ly Tam Phan , Yat Sun Or
- Applicant: Rajesh Iyengar , Yanchun Wang , Ly Tam Phan , Yat Sun Or
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, PC
- Agent Edgar W. Harlan; Carolyn S. Elmore, Esq.
- Main IPC: C07H17/08
- IPC: C07H17/08 ; A61K31/7048 ; C07D493/08

Abstract:
The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit superior antibacterial properties, particularly against Haemophilus influenzae. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
Public/Granted literature
- US20090281050A1 ANTI-BACTERIAL ACTIVITY OF 9-HYDROXY DERIVATIVES OF 6,11-BICYCLOLIDES Public/Granted day:2009-11-12
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