A patient support apparatus includes a frame, a plurality of casters coupled to the frame, and a wheel supported with respect to the frame and movable between a lowered position engaging a floor and a raised position spaced from the floor. The patient support apparatus also has a drive assembly with a first mode of operation coupled to the wheel and operable to drive the wheel to propel the patient support apparatus along the floor and a second mode of operation decoupled from the wheel so that the wheel is free to rotate when the wheel is in the lowered position and the patient support apparatus is moved along the floor. A first user input is provided to move the wheel between the raised and lowered positions and a second user input is provided to signal the drive assembly to drive the wheel.