- 专利标题： Compounds for the treatment of proliferative disorders
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申请号： US13269042申请日： 2011-10-07
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公开(公告)号： US08399435B2公开(公告)日： 2013-03-19
- 发明人: Lijun Sun , Jun Jiang , Christopher Borella , Shoujun Chen , Keizo Koya
- 申请人： Lijun Sun , Jun Jiang , Christopher Borella , Shoujun Chen , Keizo Koya
- 申请人地址： US MA Lexington
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人地址： US MA Lexington
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis; Wei Song
- 主分类号： A61K31/675
- IPC分类号： A61K31/675 ; A61K31/4439 ; A61K31/4709 ; A61K31/4725 ; A61P35/00 ; C07D275/02 ; C07D261/08 ; C07D417/10 ; C07F9/09 ; C12N5/07
摘要：
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
公开/授权文献
- US20120040937A1 COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS 公开/授权日：2012-02-16
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