发明授权
US08399706B2 Chiral tetraaminophosphonium salts, catalyst for asymmetric synthesis and method for producing chiral β-nitroalcohol
有权
手性四氨基鏻盐,用于不对称合成的催化剂和用于制备手性和次硝基醇的方法
- 专利标题: Chiral tetraaminophosphonium salts, catalyst for asymmetric synthesis and method for producing chiral β-nitroalcohol
- 专利标题(中): 手性四氨基鏻盐,用于不对称合成的催化剂和用于制备手性和次硝基醇的方法
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申请号: US12212243申请日: 2008-09-17
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公开(公告)号: US08399706B2公开(公告)日: 2013-03-19
- 发明人: Takashi Ooi , Daisuke Uraguchi
- 申请人: Takashi Ooi , Daisuke Uraguchi
- 申请人地址: JP Tokyo JP Aichi-Ken
- 专利权人: Mitsui Chemicals, Inc.,National University Corporation Nagoya University
- 当前专利权人: Mitsui Chemicals, Inc.,National University Corporation Nagoya University
- 当前专利权人地址: JP Tokyo JP Aichi-Ken
- 代理机构: Buchanan Ingersoll & Rooney PC
- 优先权: JP2007-302281 20071121
- 主分类号: C07F9/547
- IPC分类号: C07F9/547 ; C07C27/10
摘要:
A chiral tetraaminophosphonium salt represented by formula (1) and a method for producing chiral β-nitroalcohol comprising reacting an aldehyde or a ketone and a nitroalkane in the presence of the chiral tetraaminophosphonium salt represented by formula (1) and a base, or in the presence of a conjugated base of the chiral tetraaminophosphonium salt represented by formula (1): wherein R1 to R4 are independently a hydrogen atom or a monovalent hydrocarbon group; and, R1 and R2 are different groups or R3 and R4 are different groups.
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