发明授权
- 专利标题： Compounds for treating amyloidoses
- 专利标题（中）： 用于治疗淀粉样变性的化合物
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申请号： US12997673申请日： 2009-06-12
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公开(公告)号： US08409581B2公开(公告)日： 2013-04-02
- 发明人: Markus Mandler , Radmila Santic , Harald Weninger , Edith Kopinits
- 申请人： Markus Mandler , Radmila Santic , Harald Weninger , Edith Kopinits
- 申请人地址： AT Vienna
- 专利权人： Affiris AG
- 当前专利权人： Affiris AG
- 当前专利权人地址： AT Vienna
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权： ATA952/2008 20080612
- 国际申请： PCT/AT2009/000235 WO 20090612
- 国际公布： WO2009/149485 WO 20091217
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K38/08 ; C07K7/06
摘要：
The present invention relates to the use of mimotopes in the treatment of β-Amyloidoses including but not limited to Alzheimer's disease, whereby said mimotopes are able to induce the in vivo formation of antibodies directed to non truncated Aβ1-40/42, and N-terminally truncated forms AβpE3-40/42, Aβ3-40/42, Aβ11-40/42, AβpE11-40/42 and Aβ14-40/42 without interfering with physiological functions of APP signalling.
公开/授权文献
- US20110171243A1 COMPOUNDS FOR TREATING AMYLOIDOSES 公开/授权日：2011-07-14
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