发明授权
- 专利标题： Stabilized activin IIB receptor polypeptides and uses thereof
- 专利标题（中）： 稳定的激活素IIB受体多肽及其用途
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申请号： US12626375申请日： 2009-11-25
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公开(公告)号： US08410043B2公开(公告)日： 2013-04-02
- 发明人: Jeonghoon Sun , Lei-Ting Tony Tam , Mark Leo Michaels , Thomas C. Boone , Rohini Deshpande , Yue-Sheng Li , Hq Han
- 申请人： Jeonghoon Sun , Lei-Ting Tony Tam , Mark Leo Michaels , Thomas C. Boone , Rohini Deshpande , Yue-Sheng Li , Hq Han
- 申请人地址： US CA Brisbane
- 专利权人： Atara Biotherapeutics, Inc.
- 当前专利权人： Atara Biotherapeutics, Inc.
- 当前专利权人地址： US CA Brisbane
- 代理机构： Fenwick & West LLP
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/18
摘要：
The present invention provides stabilized activin IIB receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the stabilized polypeptides and proteins. Compositions and methods for treating muscle-wasting diseases and metabolic disorders are also provided.
公开/授权文献
- US20100168020A1 STABILIZED RECEPTOR POLYPEPTIDES AND USES THEREOF 公开/授权日：2010-07-01
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