发明授权
- 专利标题： Modulators of cystic fibrosis transmembrane conductance regulator
- 专利标题（中）： 囊性纤维化跨膜电导调节剂的调节剂
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申请号： US13453193申请日： 2012-04-23
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公开(公告)号： US08410132B2公开(公告)日： 2013-04-02
- 发明人: Hayley Binch , Peter D. J. Grootenhuis , Sara S Hadida Ruah , Jinglan Zhou , Anna Hazlewood , Lev T. D. Fanning
- 申请人： Hayley Binch , Peter D. J. Grootenhuis , Sara S Hadida Ruah , Jinglan Zhou , Anna Hazlewood , Lev T. D. Fanning
- 申请人地址： US MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Cambridge
- 代理商 Nancy K. Brennan
- 主分类号： A61K31/4375
- IPC分类号： A61K31/4375 ; A61P3/10 ; A61P5/18 ; A61P11/00 ; A61P25/16 ; A61P25/28 ; C07D471/04 ; C12N5/00 ; C07K1/00
摘要：
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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