- 专利标题: Methylene urea derivatives
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申请号: US12488191申请日: 2009-06-19
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公开(公告)号: US08410143B2公开(公告)日: 2013-04-02
- 发明人: Hans-Peter Buchstaller , Matthias Wiesner , Oliver Schadt , Christiane Amendt , Frank Zenke , Christian Sirrenberg , Matthias Grell , Dirk Finsinger
- 申请人: Hans-Peter Buchstaller , Matthias Wiesner , Oliver Schadt , Christiane Amendt , Frank Zenke , Christian Sirrenberg , Matthias Grell , Dirk Finsinger
- 申请人地址: DE Darmstadt
- 专利权人: Merck Patent GmbH
- 当前专利权人: Merck Patent GmbH
- 当前专利权人地址: DE Darmstadt
- 代理机构: Perkins Coie LLP
- 优先权: EP02023906 20021024
- 主分类号: A61K31/4412
- IPC分类号: A61K31/4412 ; C07D213/68
摘要:
The present invention relates to methylene urea derivatives of formula (I), the use of the compounds of formula (I) as inhibitors of raf-kinase, the use of the compounds of formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.
公开/授权文献
- US20090298885A1 METHYLENE UREA DERIVATIVES 公开/授权日:2009-12-03
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