发明授权
US08415362B2 Pyrazolyl substituted pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
有权
吡唑基取代的吡咯并[2,3-b]嘧啶作为Janus激酶抑制剂
![Pyrazolyl substituted pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors](/docs/US/2013-04-09/US08415362B2/abs.jpg.600x600.jpg)
- 专利标题： Pyrazolyl substituted pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
- 专利标题（中）： 吡唑基取代的吡咯并[2,3-b]嘧啶作为Janus激酶抑制剂
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申请号： US12138082申请日： 2008-06-12
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公开(公告)号： US08415362B2公开(公告)日： 2013-04-09
- 发明人: James D. Rodgers , Stacey Shepard , Thomas P. Maduskuie , Haisheng Wang , Nikoo Falahatpisheh , Maria Rafalski , Argyrios G. Arvanitis , Louis Storace , Ravi Kumar Jalluri
- 申请人： James D. Rodgers , Stacey Shepard , Thomas P. Maduskuie , Haisheng Wang , Nikoo Falahatpisheh , Maria Rafalski , Argyrios G. Arvanitis , Louis Storace , Ravi Kumar Jalluri
- 申请人地址： US DE Wilmington
- 专利权人： Incyte Corporation
- 当前专利权人： Incyte Corporation
- 当前专利权人地址： US DE Wilmington
- 代理机构： Fish & Richardson P.C.
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519 ; A61K31/437 ; C07D471/04 ; A61P35/00 ; A61P29/00
![Pyrazolyl substituted pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors](/abs-image/US/2013/04/09/US08415362B2/abs.jpg.150x150.jpg)
摘要：
The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines of Formula I: that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
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