- 专利标题： Triazole compounds that modulate HSP90 activity
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申请号： US13229178申请日： 2011-09-09
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公开(公告)号： US08415377B2公开(公告)日： 2013-04-09
- 发明人: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Przewloka , Shijie Zhang , Dinesh Chimmanamada , Kevin Foley , Zhenjian Du , Hao Li , David James , Howard Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- 申请人： Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Przewloka , Shijie Zhang , Dinesh Chimmanamada , Kevin Foley , Zhenjian Du , Hao Li , David James , Howard Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- 申请人地址： US MA Lexington
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人地址： US MA Lexington
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis; Mei Bai
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D403/04 ; A61K31/4196 ; A61K31/4709
摘要：
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- US20110319447A1 TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY 公开/授权日：2011-12-29