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US08415510B2 Synthesis of a PEG-6 moiety from commercial low-cost chemicals 失效
从商业低成本化学品合成PEG-6部分

  • Patent Title: Synthesis of a PEG-6 moiety from commercial low-cost chemicals
  • Patent Title (中): 从商业低成本化学品合成PEG-6部分
  • Application No.: US12918391
    Application Date: 2009-02-10
  • Publication No.: US08415510B2
    Publication Date: 2013-04-09
  • Inventor: Torgrim Engell
  • Applicant: Torgrim Engell
  • Applicant Address: GB Buckinghamshire
  • Assignee: GE Healthcare Limited
  • Current Assignee: GE Healthcare Limited
  • Current Assignee Address: GB Buckinghamshire
  • Agent Yonggang Ji
  • International Application: PCT/US2009/033620 WO 20090210
  • International Announcement: WO2009/108484 WO 20090903
  • Main IPC: C07C31/18
  • IPC: C07C31/18 C08G63/02
Synthesis of a PEG-6 moiety from commercial low-cost chemicals
Abstract:
The present invention provides novel synthesis's for obtaining a protecting group aminoxy PEG-6 linker from cost effective, and readily available starting materials and chemicals or modified polyethylene glycols. More specifically, a novel synthesis of obtaining a modified Boc-protected aminoxy PEG-6 linker was achieved so that said linker may be attached to a vector such as a peptide based fragment.
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