发明授权
- 专利标题： Gamma secretase modulators
- 专利标题（中）： 伽玛分泌酶调节剂
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申请号： US12601322申请日： 2008-05-28
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公开(公告)号： US08426403B2公开(公告)日： 2013-04-23
- 发明人: Zhaoning Zhu , William J. Greenlee , Xianhai Huang , Brian A. McKittrick , John W. Clader , Mark D. McBriar , Anandan Palani
- 申请人： Zhaoning Zhu , William J. Greenlee , Xianhai Huang , Brian A. McKittrick , John W. Clader , Mark D. McBriar , Anandan Palani
- 代理商 Susan L. Hess; Henry Jeanette; Gerard M. Devlin
- 国际申请： PCT/US2008/006734 WO 20080528
- 国际公布： WO2008/153793 WO 20081218
- 主分类号： A61K31/5365
- IPC分类号： A61K31/5365 ; A61K31/5395 ; C07D498/04 ; A61P25/28
摘要：
In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
公开/授权文献
- US20100256128A1 GAMMA SECRETASE MODULATORS 公开/授权日：2010-10-07