Invention Grant
- Patent Title: Dendritic cell marker and uses thereof
- Patent Title (中): 树突状细胞标记及其用途
-
Application No.: US12675392Application Date: 2008-08-29
-
Publication No.: US08426565B2Publication Date: 2013-04-23
- Inventor: Mireille Hanna Lahoud , Anna Irene Proietto , Irina Caminschi , Ken Shortman , Andrew Mark Lew , Li Wu , Mark Dexter Wright
- Applicant: Mireille Hanna Lahoud , Anna Irene Proietto , Irina Caminschi , Ken Shortman , Andrew Mark Lew , Li Wu , Mark Dexter Wright
- Applicant Address: AU Parkville
- Assignee: Walter and Eliza Hall Institute of Medical Research
- Current Assignee: Walter and Eliza Hall Institute of Medical Research
- Current Assignee Address: AU Parkville
- Agency: Bozicevic, Field & Francis LLP
- Agent Carol L. Francis; Shweta Chandra
- International Application: PCT/AU2008/001294 WO 20080829
- International Announcement: WO2009/026660 WO 20090305
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08
Abstract:
The present invention relates to the identification of proteins located on the cell surface of dendritic cells or precursors thereof, particularly antigen presenting dendritic cells. In particular, the present invention relates to compounds such as antibodies that bind these proteins. These compounds can be used to detect and/or enrich a subset of dendritic cells or precursors thereof. These compounds can also be used to target antigens to dendritic cells or precursors thereof to modulate a humoral and/or T cell mediated immune response to an antigen, or used to target cytotoxic agents to dendritic cells or precursors thereof involved in diseased states.
Public/Granted literature
- US20110126301A1 Dendritic Cell Marker and Uses Thereof Public/Granted day:2011-05-26
Information query
