发明授权
- 专利标题： Phenyl-heteroaryl derivatives and methods of use thereof
- 专利标题（中）： 苯基杂芳基衍生物及其使用方法
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申请号： US13028036申请日： 2011-02-15
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公开(公告)号： US08431575B2公开(公告)日： 2013-04-30
- 发明人: Devi R Gohimukkula , David Robert Jones , Ghassan Qabaja , Jeff J Zhu , Jeremy T Cooper , William K Banner , Kurt Sundermann , Muralidhar Bondlela , Mohan Rao , Pingzhen Wang , Suparna Gupta , Anitha Hari , Raju B Gowda , Robert C Andrews
- 申请人： Devi R Gohimukkula , David Robert Jones , Ghassan Qabaja , Jeff J Zhu , Jeremy T Cooper , William K Banner , Kurt Sundermann , Muralidhar Bondlela , Mohan Rao , Pingzhen Wang , Suparna Gupta , Anitha Hari , Raju B Gowda , Robert C Andrews
- 申请人地址： US NC High Point
- 专利权人： TransTech Pharma, Inc.
- 当前专利权人： TransTech Pharma, Inc.
- 当前专利权人地址： US NC High Point
- 代理商 Samuel B. Rollins
- 主分类号： A01N43/58
- IPC分类号： A01N43/58 ; A01N43/60 ; A61K31/50 ; A61K31/495
摘要：
The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the use of such compounds and/or pharmaceutical compositions in treating RAGE-mediated diseases.
公开/授权文献
- US20110230458A1 PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF 公开/授权日：2011-09-22
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