发明授权
- 专利标题： Kinase inhibitor with improved solubility profile
- 专利标题（中）： 具有改善溶解度特征的激酶抑制剂
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申请号： US13551680申请日： 2012-07-18
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公开(公告)号： US08436179B2公开(公告)日： 2013-05-07
- 发明人: Michael R. Michaelides , Michael L. Curtin , James H. Holms , Douglas H. Steinman
- 申请人： Michael R. Michaelides , Michael L. Curtin , James H. Holms , Douglas H. Steinman
- 申请人地址： US IL North Chicago
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： US IL North Chicago
- 代理商 Susan L. Steele
- 主分类号： C07D513/02
- IPC分类号： C07D513/02 ; A61K31/44
摘要：
4-Amino-N-[3-(diethylamino)propyl]-3-(4-{[(3-fluorophenyl)carbamoyl]amino}phenyl)thieno[3,2-c]pyridine-7-carboxamide which inhibits protein kinases such as Aurora-kinases and the VEGFR and PDGFR families of kinases, with an improved aqueous solubility profile, compositions containing 4-amino-N-[3-(diethylamino)propyl]-3-(4-{[(3-fluorophenyl)carbamoyl]amino}phenyl)thieno[3,2-c]pyridine-7-carboxamide and methods of treating diseases using 4-amino-N-[3-(diethylamino)propyl]-3-(4-{[(3-fluorophenyl)carbamoyl]amino}phenyl)thieno[3,2-c]pyridine-7-carboxamide are disclosed.
公开/授权文献
- US20130023555A1 KINASE INHIBITOR WITH IMPROVED SOLUBILITY PROFILE 公开/授权日：2013-01-24
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