发明授权
US08449881B2 Anti-α-enolase I antibodies for diagnosis and treatment of α-enolase I-associated diseases
有权
用于诊断和治疗α-烯醇酶I相关疾病的抗α-烯醇酶I抗体
- 专利标题: Anti-α-enolase I antibodies for diagnosis and treatment of α-enolase I-associated diseases
- 专利标题(中): 用于诊断和治疗α-烯醇酶I相关疾病的抗α-烯醇酶I抗体
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申请号: US12695627申请日: 2010-01-28
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公开(公告)号: US08449881B2公开(公告)日: 2013-05-28
- 发明人: Sy-Jye Leu , Yi-Yuan Yang , Neng-Yao Shih , I-Jen Huang , Ko-Jiunn Liu , Yu-Ching Lee , Yung-Leun Shih , Yu-Jia Chang , Bor-Yu Tsai , Yuan-Soon Ho
- 申请人: Sy-Jye Leu , Yi-Yuan Yang , Neng-Yao Shih , I-Jen Huang , Ko-Jiunn Liu , Yu-Ching Lee , Yung-Leun Shih , Yu-Jia Chang , Bor-Yu Tsai , Yuan-Soon Ho
- 申请人地址: TW Taipei
- 专利权人: Taipei Medical University
- 当前专利权人: Taipei Medical University
- 当前专利权人地址: TW Taipei
- 代理机构: WPAT, P.C.
- 代理商 Anthony King
- 主分类号: A61K39/395
- IPC分类号: A61K39/395
摘要:
The invention relates to antibodies against α-enolase I, their pharmaceutical compositions and diagnosis and treatment uses. Particularly, the invention provides polyclonal anti-α-enolase I antibodies and monoclonal single-chain variable fragment (scFv) anti-α-enolase antibodies, pharmaceutical compositions containing the same and their uses in uses in diagnosis and treatment of cancers, autoimmune disorders, ischemia and bacterial infection.
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