发明授权
US08450441B2 Synthetic N-linked sialo-glycan-containing polymer and method for producing the same
失效
合成的N-连接唾液酸聚糖聚合物及其制备方法
- 专利标题： Synthetic N-linked sialo-glycan-containing polymer and method for producing the same
- 专利标题（中）： 合成的N-连接唾液酸聚糖聚合物及其制备方法
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申请号： US12666482申请日： 2008-06-24
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公开(公告)号： US08450441B2公开(公告)日： 2013-05-28
- 发明人: Taiichi Usui , Takeomi Murata , Takashi Suzuki , Ilpal Jwa , Yusuke Ohba , Tomoki Hamamoto , Toshitada Noguchi
- 申请人： Taiichi Usui , Takeomi Murata , Takashi Suzuki , Ilpal Jwa , Yusuke Ohba , Tomoki Hamamoto , Toshitada Noguchi
- 申请人地址： JP Shizuoka JP Shizuoka JP Chiba
- 专利权人： National University Corporation Shizuoka University,Shizuoka Prefectural Universities Corporation,Yamasa Corporation
- 当前专利权人： National University Corporation Shizuoka University,Shizuoka Prefectural Universities Corporation,Yamasa Corporation
- 当前专利权人地址： JP Shizuoka JP Shizuoka JP Chiba
- 代理机构： Pearne & Gordon LLP
- 优先权： JP2007-170079 20070628
- 国际申请： PCT/JP2008/061429 WO 20080624
- 国际公布： WO2009/001805 WO 20081231
- 主分类号： C08F251/00
- IPC分类号： C08F251/00 ; C07H15/06 ; C12Q1/70
摘要：
A polymer containing an N-linked sialo-glycan wherein a sialo-glycan is condensed to a γ-polyglutamic acid using a chemical compound having an amino group on one end and a carboxyl group on another end and represented by the structural formula (I). Formula (I) (In the formula, Z means a hydroxy group or a residue represented by the formula (II), and n represents an integer of 10 or more, with the proviso that any one or more of the Z's is represented by the formula in (II).) Formula (II) (In the formula, X means a hydroxy group or an acetylamino group, Y1 and Y2 mean a hydroxyl group or an N-acetylneuraminic acid residue, L means a hydrocarbon, an m represents 0 or an integer of 1 or 2, with the proviso that Y1 and Y2 are not the same.)
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