发明授权
- 专利标题: Adhesive preparation
- 专利标题(中): 粘合剂制备
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申请号: US12227066申请日: 2007-08-01
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公开(公告)号: US08455376B2公开(公告)日: 2013-06-04
- 发明人: Kiyomi Tsuruda , Shinji Yamasoto , Kouki Shoho , Masaru Nakanishi
- 申请人: Kiyomi Tsuruda , Shinji Yamasoto , Kouki Shoho , Masaru Nakanishi
- 申请人地址: JP Tosu-Shi, Saga
- 专利权人: Hisamitsu Pharmaceutical Co., Inc.
- 当前专利权人: Hisamitsu Pharmaceutical Co., Inc.
- 当前专利权人地址: JP Tosu-Shi, Saga
- 代理机构: Nath, Goldberg & Meyer
- 代理商 Sheldon M. McGee
- 优先权: JPP2006-213670 20060804
- 国际申请: PCT/JP2007/065067 WO 20070801
- 国际公布: WO2008/016077 WO 20080207
- 主分类号: B32B25/02
- IPC分类号: B32B25/02 ; A61F13/00 ; A61L15/16 ; A61K9/70
摘要:
An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.
公开/授权文献
- US20090149794A1 Adhesive Preparation 公开/授权日:2009-06-11