发明授权
- 专利标题： Imidazopyrazine Syk inhibitors
- 专利标题（中）： 咪唑吡嗪Syk抑制剂
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申请号： US12632140申请日： 2009-12-07
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公开(公告)号： US08455493B2公开(公告)日： 2013-06-04
- 发明人: Scott A. Mitchell , Kevin S. Currie , Peter A. Blomgren , Jeffrey E. Kropf , Seung H. Lee , Jianjun Xu , Douglas G. Stafford , James P. Harding , Antonio J. M. Barbosa, Jr. , Zhongdong Zhao , Soumya Mitra , David M. Armistead
- 申请人： Scott A. Mitchell , Kevin S. Currie , Peter A. Blomgren , Jeffrey E. Kropf , Seung H. Lee , Jianjun Xu , Douglas G. Stafford , James P. Harding , Antonio J. M. Barbosa, Jr. , Zhongdong Zhao , Soumya Mitra , David M. Armistead
- 申请人地址： US CA Foster City
- 专利权人： Gilead Connecticut, Inc.
- 当前专利权人： Gilead Connecticut, Inc.
- 当前专利权人地址： US CA Foster City
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K31/495
- IPC分类号： A61K31/495
摘要：
Certain imidazopyrazines of Formula (I) and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.
公开/授权文献
- US20100222323A1 IMIDAZOPYRAZINE SYK INHIBITORS 公开/授权日：2010-09-02
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