发明授权
- 专利标题: Alkyne antagonists of lysophosphatidic acid receptors
- 专利标题(中): 溶血磷脂酸受体的炔烃拮抗剂
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申请号: US13133636申请日: 2009-12-10
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公开(公告)号: US08455499B2公开(公告)日: 2013-06-04
- 发明人: John Howard Hutchinson , Thomas Jon Seiders , Jeannie M. Arruda
- 申请人: John Howard Hutchinson , Thomas Jon Seiders , Jeannie M. Arruda
- 申请人地址: US NJ Princeton
- 专利权人: Amira Pharmaceuticals, Inc.
- 当前专利权人: Amira Pharmaceuticals, Inc.
- 当前专利权人地址: US NJ Princeton
- 代理商 Maureen S. Gibbons
- 国际申请: PCT/US2009/067527 WO 20091210
- 国际公布: WO2010/068775 WO 20100617
- 主分类号: C07D239/26
- IPC分类号: C07D239/26 ; C07D417/10 ; C07D277/10 ; C07D261/14 ; A61K31/426 ; A61K31/422 ; A61K31/42
摘要:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
公开/授权文献
- US20110301134A1 ALKYNE ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS 公开/授权日:2011-12-08
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