发明授权
US08461178B2 Naphthyridine derivatives and the use thereof as kinase inhibitors
有权
萘啶衍生物及其作为激酶抑制剂的用途
- 专利标题： Naphthyridine derivatives and the use thereof as kinase inhibitors
- 专利标题（中）： 萘啶衍生物及其作为激酶抑制剂的用途
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申请号： US12953680申请日： 2010-11-24
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公开(公告)号： US08461178B2公开(公告)日： 2013-06-11
- 发明人: Tilmann Schuster , Matthias Gerlach , Irene Seipelt , Emmanuel Polymeropoulos , Gilbert Mueller , Eckhard Guenther , Pascal Marchand , Julien Defaux
- 申请人： Tilmann Schuster , Matthias Gerlach , Irene Seipelt , Emmanuel Polymeropoulos , Gilbert Mueller , Eckhard Guenther , Pascal Marchand , Julien Defaux
- 申请人地址： DE Frankfurt
- 专利权人： Aeterna Zentaris GmbH
- 当前专利权人： Aeterna Zentaris GmbH
- 当前专利权人地址： DE Frankfurt
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权： EP09177132 20091126
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D471/02
摘要：
The present invention relates to kinase modulators of the naphthyridine type and to the preparation and use thereof as medicaments for the modulation of misdirected cellular signal transduction processes, in particular for influencing the function of tyrosine and serine/threonine kinases and for the treatment of malignant or benign tumors and other disorders based on pathological cell proliferation, such as, for example, restenosis, psoriasis, arteriosclerosis and cirrhosis of the liver.
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