Invention Grant
- Patent Title: TFPI inhibitors and methods of use
- Patent Title (中): TFPI抑制剂和使用方法
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Application No.: US12643818Application Date: 2009-12-21
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Publication No.: US08466108B2Publication Date: 2013-06-18
- Inventor: Michael Dockal , Hartmut Ehrlich , Friedrich Scheiflinger , Ulf Reimer , Ulrich Reineke , Thomas Polakowski , Eberhard Schneider
- Applicant: Michael Dockal , Hartmut Ehrlich , Friedrich Scheiflinger , Ulf Reimer , Ulrich Reineke , Thomas Polakowski , Eberhard Schneider
- Applicant Address: US IL Deerfield CH Glattpark (Opfikon)
- Assignee: Baxter International Inc.,Baxter Healthcare SA
- Current Assignee: Baxter International Inc.,Baxter Healthcare SA
- Current Assignee Address: US IL Deerfield CH Glattpark (Opfikon)
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K38/36
- IPC: A61K38/36 ; A61K38/37 ; A61K38/10 ; A61K38/00 ; A61K38/04 ; A61K38/16 ; C07K14/745 ; C07K14/755
Abstract:
The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, and/or treat a blood coagulation disorder in a subject.
Public/Granted literature
- US20100173847A1 TFPI INHIBITORS AND METHODS OF USE Public/Granted day:2010-07-08
Information query
IPC分类:
