Invention Grant
US08486966B2 9-(pyrazol-3-yl)-9H-purine-2-amine and 3-(pyrazol-3-yl) -3H-imidazo[4,5-B] pyridin-5-amine derivatives and their use for the treatment of cancer
失效
9-（吡唑-3-基）-9H-嘌呤-2-胺和3-（吡唑-3-基）-3H-咪唑并[4,5-B]吡啶-5-胺衍生物及其用于治疗 的癌症
![9-(pyrazol-3-yl)-9H-purine-2-amine and 3-(pyrazol-3-yl) -3H-imidazo[4,5-B] pyridin-5-amine derivatives and their use for the treatment of cancer](/docs/US/2013-07-16/US08486966B2/abs.jpg.600x600.jpg)
- Patent Title: 9-(pyrazol-3-yl)-9H-purine-2-amine and 3-(pyrazol-3-yl) -3H-imidazo[4,5-B] pyridin-5-amine derivatives and their use for the treatment of cancer
- Patent Title (中): 9-（吡唑-3-基）-9H-嘌呤-2-胺和3-（吡唑-3-基）-3H-咪唑并[4,5-B]吡啶-5-胺衍生物及其用于治疗 的癌症
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Application No.: US12598473Application Date: 2008-05-02
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Publication No.: US08486966B2Publication Date: 2013-07-16
- Inventor: Audrey Davies , Stephanos Ioannidis , Michelle Lamb , Mei Su , Tao Wang , Hai-Jun Zhang
- Applicant: Audrey Davies , Stephanos Ioannidis , Michelle Lamb , Mei Su , Tao Wang , Hai-Jun Zhang
- Applicant Address: SE Sodertalje
- Assignee: Astrazeneca AB
- Current Assignee: Astrazeneca AB
- Current Assignee Address: SE Sodertalje
- International Application: PCT/GB2008/050321 WO 20080502
- International Announcement: WO2008/135785 WO 20081113
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D471/02 ; C07D491/02 ; C07D498/02
![9-(pyrazol-3-yl)-9H-purine-2-amine and 3-(pyrazol-3-yl) -3H-imidazo[4,5-B] pyridin-5-amine derivatives and their use for the treatment of cancer](/abs-image/US/2013/07/16/US08486966B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These compounds provide a treatment for myeloproliferative disorders and cancer.
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