发明授权
- 专利标题： KAT II inhibitors
- 专利标题（中）： KAT II抑制剂
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申请号： US13307140申请日： 2011-11-30
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公开(公告)号： US08487104B2公开(公告)日： 2013-07-16
- 发明人: Amy B Dounay , Christopher J Helal , Jamison B Tuttle , Patrick R Verhoest
- 申请人： Amy B Dounay , Christopher J Helal , Jamison B Tuttle , Patrick R Verhoest
- 申请人地址： US NY New York
- 专利权人： Pfizer Inc.
- 当前专利权人： Pfizer Inc.
- 当前专利权人地址： US NY New York
- 代理商 Feng Shao
- 主分类号： C07D215/58
- IPC分类号： C07D215/58
摘要：
The present invention relates to compounds 3-amino-1-hydroxy-2-oxo-1,2,3, 4-tetrahydroquinoline-7-carbonitrile, 3-amino-1-hydroxy-7-(2-methoxyethoxy)-3,4-dihydroquinolin-2(1H)-one, and 3-amino-1-hydroxy-7-[(1S)-2-methoxy-1-methylethoxy]-3,4-dihydroquinolin-2(1H)-one, including racemic mixtures and resolved enantiomers thereof, to pharmaceutically acceptable salts thereof, and to the treatment of cognitive deficits associated with schizophrenia and other psychiatric, neurodegenerative and/or neurological disorders in mammals, including humans.
公开/授权文献
- US20120142729A1 KAT ll INHIBITORS 公开/授权日：2012-06-07
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