A method for controlling uplink power is provided, which is used for implementing the uplink power control of the virtual multiple input multiple output system, so as to save the system resource. The method includes: determining at least two user equipments being paired in a virtual multiple input multiple output system; and in accordance with the orthogonality of the at least two user equipments, adjusting at least the power of one of the user equipments. In addition, a device for implementing the method is provided.