Invention Grant
- Patent Title: Sugar chain added GLP-1 peptide
- Patent Title (中): 糖链添加GLP-1肽
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Application No.: US13152082Application Date: 2011-06-02
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Publication No.: US08507429B2Publication Date: 2013-08-13
- Inventor: Yasuhiro Kajihara , Takashi Tsuji , Izumi Sakamoto , Yuri Nambu , Kazuhiro Fukae , Katsunari Tezuka , Hiroaki Asai
- Applicant: Yasuhiro Kajihara , Takashi Tsuji , Izumi Sakamoto , Yuri Nambu , Kazuhiro Fukae , Katsunari Tezuka , Hiroaki Asai
- Applicant Address: JP Kyoto-Shi, Kyoto
- Assignee: Glytech, Inc.
- Current Assignee: Glytech, Inc.
- Current Assignee Address: JP Kyoto-Shi, Kyoto
- Agency: Brinks Hofer Gilson & Lione
- Priority: JP2007-160951 20070619
- Main IPC: A61K38/26
- IPC: A61K38/26 ; A61K38/14
Abstract:
The present invention relates to an oligosaccharide chain added GLP-1 peptide that has higher stability in blood than that of GLP-1 and, preferably, exhibits higher activity of controlling blood-sugar levels than that of GLP-1. The present invention relates to an oligosaccharide chain added GLP-1 peptide having GLP-1 activity, wherein at least one amino acid is substituted with an oligosaccharide chain added amino acid, in: (a) GLP-1; (b) a peptide having the amino acid sequence of GLP-1 with deletion, substitution or addition of one or several amino acids; or (c) a GLP-1 analog.
Public/Granted literature
- US20110245166A1 SUGAR CHAIN ADDED GLP-1 PEPTIDE Public/Granted day:2011-10-06
Information query
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