发明授权
- 专利标题： SDF-1 delivery for treating ischemic tissue
- 专利标题（中）： 用于治疗缺血组织的SDF-1递送
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申请号： US13556595申请日： 2012-07-24
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公开(公告)号： US08513213B2公开(公告)日： 2013-08-20
- 发明人: Marc S. Penn , Rahul Aras , Joseph Pastore , Timothy J. Miller
- 申请人： Marc S. Penn , Rahul Aras , Joseph Pastore , Timothy J. Miller
- 申请人地址： US OH Cleveland US OH Cleveland
- 专利权人： The Cleveland Clinic Foundation,Juventas Therapeutics, Inc.
- 当前专利权人： The Cleveland Clinic Foundation,Juventas Therapeutics, Inc.
- 当前专利权人地址： US OH Cleveland US OH Cleveland
- 代理机构： Woodcock Washburn LLP
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C12N15/00
摘要：
A method of treating a cardiomyopathy in a subject includes administering directly to or expressing locally in a weakened, ischemic, and/or peri-infarct region of myocardial tissue of the subject an amount of SDF-1 effective to cause functional improvement in at least one of the following parameters: left ventricular volume, left ventricular area, left ventricular dimension, cardiac function, 6-minute walk test, or New York Heart Association (NYHA) functional classification.
公开/授权文献
- US20120289585A1 SDF-1 Delivery For Treating Ischemic Tissue 公开/授权日：2012-11-15
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