发明授权
- 专利标题： Pyrimidine compounds and methods of making and using same
- 专利标题（中）： 嘧啶化合物及其制备和使用方法
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申请号： US13139009申请日： 2009-12-11
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公开(公告)号： US08513242B2公开(公告)日： 2013-08-20
- 发明人: Phoebe Chiang , Shomir Ghosh
- 申请人： Phoebe Chiang , Shomir Ghosh
- 申请人地址： US MD Bethesda
- 专利权人： Cystic Fibrosis Foundation Therapeutics, Inc.
- 当前专利权人： Cystic Fibrosis Foundation Therapeutics, Inc.
- 当前专利权人地址： US MD Bethesda
- 代理机构： Goodwin Procter LLP
- 国际申请： PCT/US2009/067667 WO 20091211
- 国际公布： WO2010/068863 WO 20100617
- 主分类号： A61K31/535
- IPC分类号： A61K31/535 ; A61K31/505
摘要：
Disclosed herein are pyrimidinyl compounds that are contemplated to be modulators of cystic fibrosis transmembrane regulators (CFTR), and methods of making and using same. Also provided are pharmaceutical compositions and methods of treating disorders associated with cystic fibrosis transmembrane regulators, such as airway inflammation, cystic fibrosis, and the like.
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