发明授权
- 专利标题: P38 kinase inhibiting agents
- 专利标题(中): P38激酶抑制剂
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申请号: US13266043申请日: 2010-04-26
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公开(公告)号: US08513289B2公开(公告)日: 2013-08-20
- 发明人: Hiroo Koyama , Soumya P. Sahoo , Ginger Xu-Qiang Yang , Daniel J. Miller
- 申请人: Hiroo Koyama , Soumya P. Sahoo , Ginger Xu-Qiang Yang , Daniel J. Miller
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 代理商 Maria V. Marucci
- 国际申请: PCT/US2010/032345 WO 20100426
- 国际公布: WO2010/129208 WO 20101111
- 主分类号: A61K31/4245
- IPC分类号: A61K31/4245 ; A61K31/433 ; C07D285/08 ; C07D207/333
摘要:
Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: Formula (I); are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, COPD, ARDS, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.
公开/授权文献
- US20120040999A1 P38 KINASE INHIBITING AGENTS 公开/授权日:2012-02-16
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