发明授权
US08519096B2 Citrullinated peptides for diagnosing and prognosing rheumatoid arthritis
有权
用于诊断和预测类风湿性关节炎的瓜氨酸肽
- 专利标题： Citrullinated peptides for diagnosing and prognosing rheumatoid arthritis
- 专利标题（中）： 用于诊断和预测类风湿性关节炎的瓜氨酸肽
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申请号： US13239329申请日： 2011-09-21
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公开(公告)号： US08519096B2公开(公告)日： 2013-08-27
- 发明人: Nicholas Chi-Kwan Ling , Shui Long Wang , Dunrui Wang , Sharat Singh
- 申请人： Nicholas Chi-Kwan Ling , Shui Long Wang , Dunrui Wang , Sharat Singh
- 申请人地址： CH Vevey
- 专利权人： Nestec S.A.
- 当前专利权人： Nestec S.A.
- 当前专利权人地址： CH Vevey
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 主分类号： G01N33/531
- IPC分类号： G01N33/531 ; G01N33/533 ; C07K17/00
摘要：
The present invention provides novel citrullinated peptides, their use in methods for aiding, assisting, improving, or facilitating the diagnosis or prognosis of rheumatic diseases such as rheumatoid arthritis (RA), and methods for identifying novel citrullinated peptides that are immunoreactive with anti-citrullinated protein antibodies (ACPAs). The present invention also provides methods for detecting rheumatoid factor (RF) using novel RF detection reagents as a means to aid, assist, improve, or facilitate the diagnosis or prognosis of rheumatic diseases such as RA. Kits comprising at least one of the novel citrullinated peptides and/or RF detection reagents of the present invention are also provided.
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