发明授权
- 专利标题： Simian subfamily B adenoviruses SAdV-28, -27, -29, -32, -33, and -35 and uses thereof
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申请号： US12744375申请日： 2008-11-24
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公开(公告)号： US08524219B2公开(公告)日： 2013-09-03
- 发明人: Soumitra Roy , James M Wilson , Luc H Vandenberghe
- 申请人： Soumitra Roy , James M Wilson , Luc H Vandenberghe
- 申请人地址： US PA Philadelphia
- 专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Howson & Howson LLP
- 国际申请： PCT/US2008/013065 WO 20081124
- 国际公布： WO2009/073103 WO 20090611
- 主分类号： A61K35/76
- IPC分类号： A61K35/76 ; A61K48/00 ; C12N7/01 ; C12N15/00 ; C12N15/34
摘要：
A recombinant vector comprises simian adenovirus 28, simian adenovirus 27, simian adenovirus 32, simian adenovirus 33, and/or simian adenovirus 35 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses one or more simian adenovirus-28, -27, -32, -33, or -35 genes is also disclosed. Methods of using the vectors and cell lines are provided.