发明授权
US08524655B2 Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders
有权
使用SCF和G-CSF治疗脑缺血和神经系统疾病
- 专利标题: Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders
- 专利标题(中): 使用SCF和G-CSF治疗脑缺血和神经系统疾病
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申请号: US12714068申请日: 2010-02-26
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公开(公告)号: US08524655B2公开(公告)日: 2013-09-03
- 发明人: Li-Ru Zhao , John Kessler , Seema Singhal , Jayesh Mehta
- 申请人: Li-Ru Zhao , John Kessler , Seema Singhal , Jayesh Mehta
- 申请人地址: US IL Evanston
- 专利权人: Northwestern University
- 当前专利权人: Northwestern University
- 当前专利权人地址: US IL Evanston
- 代理机构: Marshall, Gerstein & Borun LLP
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K38/18
摘要:
The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.
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