Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders
    2.
    发明授权
    Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders 有权
    使用SCF和G-CSF治疗脑缺血和神经系统疾病

    公开(公告)号:US08524655B2

    公开(公告)日:2013-09-03

    申请号:US12714068

    申请日:2010-02-26

    IPC分类号: A61K38/00 A61K38/18

    摘要: The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.

    摘要翻译: 本发明涉及单核细胞因子(SCF)多肽与粒细胞集落刺激因子(G-CSF)多肽联合用于预防或治疗脑缺血或神经障碍后脑损伤的用途。 更具体地,本发明提供通过单独施用SCF多肽并与G-CSF多肽组合来改善中风后神经功能和结局的方法。 这种治疗可以单独使用,也可以与其他公知的治疗哺乳动物脑缺血和神经障碍的方法组合使用。

    Use of SCF and G-CSF in the Treatment of Cerebral Ischemia and Neurological Disorders
    4.
    发明申请
    Use of SCF and G-CSF in the Treatment of Cerebral Ischemia and Neurological Disorders 有权
    使用SCF和G-CSF治疗脑缺血和神经障碍

    公开(公告)号:US20100286039A1

    公开(公告)日:2010-11-11

    申请号:US12714068

    申请日:2010-02-26

    IPC分类号: A61K38/18 A61P25/00

    摘要: The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.

    摘要翻译: 本发明涉及单核细胞因子(SCF)多肽与粒细胞集落刺激因子(G-CSF)多肽联合用于预防或治疗脑缺血或神经障碍后脑损伤的用途。 更具体地,本发明提供通过单独施用SCF多肽并与G-CSF多肽组合来改善中风后神经功能和结局的方法。 这种治疗可以单独使用,也可以与其他公知的治疗哺乳动物脑缺血和神经障碍的方法组合使用。