发明授权
- 专利标题： Methods of producing anti-IL-22RA antibodies
- 专利标题（中）： 产生抗IL-22RA抗体的方法
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申请号： US13349380申请日： 2012-01-12
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公开(公告)号： US08536309B2公开(公告)日： 2013-09-17
- 发明人: Wenfeng Xu , Wayne R. Kindsvogel , Yasmin A. Chandrasekher , Stacey R. Dillon , Joyce M. Lehner , Anthony W. Siadak , Pallavur V. Sivakumar , Margaret D. Moore
- 申请人： Wenfeng Xu , Wayne R. Kindsvogel , Yasmin A. Chandrasekher , Stacey R. Dillon , Joyce M. Lehner , Anthony W. Siadak , Pallavur V. Sivakumar , Margaret D. Moore
- 申请人地址： US WA Seattle
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 当前专利权人地址： US WA Seattle
- 代理机构： Nelson Mullins Riley & Scarborough LLP
- 代理商 Jane E. Remillard, Esq.; Jill Gorny Sloper, Esq.
- 主分类号： C07K16/00
- IPC分类号： C07K16/00
摘要：
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners.
公开/授权文献
- US20120156210A1 METHODS OF TREATMENT USING ANTI-IL-22RA ANTIBODIES 公开/授权日：2012-06-21
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