发明授权
US08536330B2 Intermediates for the preparation of HMG-CoA reductase inhibitors
失效
用于制备HMG-CoA还原酶抑制剂的中间体
- 专利标题： Intermediates for the preparation of HMG-CoA reductase inhibitors
- 专利标题（中）： 用于制备HMG-CoA还原酶抑制剂的中间体
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申请号： US13642209申请日： 2011-04-21
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公开(公告)号： US08536330B2公开(公告)日： 2013-09-17
- 发明人: Vishwesh Pravinchandra Pandya , Santosh Richhariya , Prabhakar Divya , Hashim Nizar Poovanathil Nagoor Meeran , Neera Tewari
- 申请人： Vishwesh Pravinchandra Pandya , Santosh Richhariya , Prabhakar Divya , Hashim Nizar Poovanathil Nagoor Meeran , Neera Tewari
- 申请人地址： IN New Delhi
- 专利权人： Ranbaxy Laboratories Limited
- 当前专利权人： Ranbaxy Laboratories Limited
- 当前专利权人地址： IN New Delhi
- 优先权： IN980/DEL/2010 20100423
- 国际申请： PCT/IB2011/051757 WO 20110421
- 国际公布： WO2011/132172 WO 20111027
- 主分类号： C07D417/12
- IPC分类号： C07D417/12
摘要：
The present invention provides a process for preparing novel intermediates of Formula wherein, R1 can be hydrogen, C1-C4 alkyl, halogen, nitro, hydroxy, or C1-C4 alkoxy; Rx can be selected from hydrophobic residue of HMG-CoA reductase inhibitors; which can be effectively used for the preparation of HMG-CoA reductase inhibitors such as rosuvastatin and pharmaceutically acceptable salts thereof.
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