发明授权
US08540969B2 Aerosol dispersions of particles with active pharmaceutical ingredients
有权
具有活性药物成分的颗粒的气溶胶分散体
- 专利标题： Aerosol dispersions of particles with active pharmaceutical ingredients
- 专利标题（中）： 具有活性药物成分的颗粒的气溶胶分散体
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申请号： US12596508申请日： 2008-04-18
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公开(公告)号： US08540969B2公开(公告)日： 2013-09-24
- 发明人: Andrew Loxley , Ismar Dizdarevic , Mark Mitchnick
- 申请人： Andrew Loxley , Ismar Dizdarevic , Mark Mitchnick
- 申请人地址： US PA Bethlehem
- 专利权人： Particle Sciences, Inc.
- 当前专利权人： Particle Sciences, Inc.
- 当前专利权人地址： US PA Bethlehem
- 代理机构： Licata & Tyrrell P.C.
- 国际申请： PCT/US2008/060742 WO 20080418
- 国际公布： WO2008/131170 WO 20081030
- 主分类号： A61K9/12
- IPC分类号： A61K9/12 ; A61K9/127 ; A61K9/133 ; A61K9/14
摘要：
Aerosols containing a plurality of aqueous droplets, each droplet containing on average at least one essentially-neutral particle sized to fit within the droplet are provided. Aerosols wherein an active pharmaceutical ingredient is attached to, or otherwise incorporated in the essentially neutral particles are also provided. Methods for administering an active pharmaceutical ingredient to a subject in need thereof via inhalation of these aerosols, preferably via nebulizer, are also provided.
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